Creative Biolabs, a biotechnology service provider, has announced an exclusive webinar titled “Modeling T Cell Dysfunction in Tumor Microenvironments,” scheduled for September 1, 2026, at 10:00 AM EDT. The live virtual event will feature a keynote presentation by Greg M. Delgoffe, Ph.D., Professor of Immunology at the University of Pittsburgh and Director of the Tumor Microenvironment Center at the UPMC Hillman Cancer Center.
The webinar addresses a critical challenge in oncology: understanding how the tumor microenvironment (TME) contributes to T cell dysfunction and immune evasion. As tumors progress, they create a metabolically hostile environment characterized by nutrient depletion and accumulation of immunosuppressive byproducts. These conditions impair immune cell function, leading to reduced responses to cancer immunotherapies. By modeling these complex conditions, researchers can gain insights that may improve therapeutic strategies.
Dr. Delgoffe’s research focuses on the intersection of tumor metabolism and immune regulation. The webinar will explore innovative approaches to replicate TME conditions using advanced preclinical testing services and robust in vivo and in vitro models. These systems allow researchers to mimic metabolic stress conditions, providing a more accurate platform for studying immune suppression and therapeutic responses.
“Understanding how metabolic conditions within tumors influence immune-cell behavior is increasingly important in immuno-oncology,” said a senior scientific director at Creative Biolabs. “Dr. Delgoffe’s work provides an important perspective on how researchers can model these conditions and investigate target discovery and validation.”
The webinar will cover key topics including how tumor metabolic environments drive immune suppression and T cell exhaustion, strategies for modeling TME conditions in preclinical research, mechanisms underlying T cell exhaustion, and how immunometabolism insights can guide therapeutic approaches.
This event is particularly relevant for cancer immunology researchers, pharmaceutical and biotechnology professionals, and R&D teams focused on oncology drug discovery. The webinar aims to bridge the gap between basic immunology and translational applications, offering practical knowledge for improving cancer treatments.
For more details and registration, visit the webinar page.
